【摘要】 目的测定慢性荨麻疹患者甲状腺功能并作相关性分析。方法采用放射免疫法对54例慢性荨麻疹患者及48例健康对照组的甲状腺功能及甲状腺自身抗体进行检测。结果54例患者中抗甲状腺球蛋白抗体(TG-Ab)及抗甲状腺微粒体抗体(TM-Ab)水平均显著高于对照组(P均<0.01);但2组的三碘甲状腺原氨酸(T3)、甲状腺素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)比较无显著性差异。结论部分慢性荨麻疹患者的甲状腺功能、甲状腺自身抗体异常,提示慢性荨麻疹患者的发病可能和甲状腺功能紊乱有关。更多还原

【Abstract】 Objective It is to determine the serum levels of thyroid autoimmunity in patients with chronic urticaria,and to analyze their correlation.Methods The thyroid action and antithyroid autoantibodies in 54 patients with chronic urticaria and 48 healthy controls were detected by radioimmunoassay methods.Results The serum levels of antithyroglobulin antibody (TG-Ab) and antithyromicrosome antibody(TM-Ab) in patients with chronic urticaria were significantly higher than those in healthy controls(P<0.01).There were no significant differences on the levels of other parameters(T3,T4,FT3 and FT4) between the two groups.Conclusion The thyroid function,antithyroid autoantibodies are abnormal in part patients with chronic urticaria,it suggest that the pathogenesis of chronic urticaria may be correlated with thyroid functional disorder.更多还原