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脂蛋白肾病一例报道及其超微结构分析

A Report on and an Ultra-structure Analysis of a Case of Lipoprotein Glomerulopathy

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【作者】 吴金浪陶瑜周胜利林玉坤郑树森郑文辉吴强

【Author】 WU Jin-lang1, TAO Yu2, ZHOU Sheng-li1, LIN Yu-kun1, ZHENG Shu-sen1, ZHENG Wen-hui1, WU Qiang1 (1. Electron-Microscope Lab, Sun Yat-sen Medical School, Sun Yat-sen University, Guangzhou 510080, China; 2. Pathology Department, No.1 Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China)

【机构】 中山大学中山医学院电镜室中山大学附属第一医院病理科

【摘要】 [目的]报告一例脂蛋白肾病,并分析其超微结构特点.[方法]分析脂蛋白肾病患者的临床表现、实验室结果,以及肾活检病理检查结果.[结果]该病例经病理检查,结合临床特点证实为脂蛋白肾病.[结论]诊断脂蛋白肾病除根据临床表现外,还应结合光镜病理和超微病理特征,而毛细血管袢中广泛性脂蛋白栓子形成及ApoB、ApoE染色阳性,是诊断的关键依据.

【Abstract】 [Objective] One case of lipoprotein glomerulopathy (LPN) is reported and its pathological features under electronic microscopy are analyzed. [Method] Data on the patient including clinical manifestations, laboratory examination results, and kidney biopsy pathological examination results, are analyzed. [Results] The case was diagnosed as lipoprotein glomerulopathy. [Conclusion] Diagnosis of LPN should be based on clinical manifestations and renal biopsy, including examination of ultrastructure characteristics. Extensive glomerular capillary thrombosis stained positive for ApoB and ApoE plays a key role in the diagnosis of LPN.

【关键词】 脂蛋白肾病超微结构ApoBApoE
【Key words】 lipoprotein glomerulopathyultra-structureApoBApoE
  • 【文献出处】 五邑大学学报(自然科学版) ,Journal of Wuyi University(Natural Science Edition) , 编辑部邮箱 ,2009年02期
  • 【分类号】R692.3
  • 【被引频次】2
  • 【下载频次】147
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