【摘要】 为探讨干扰素γ诱导蛋白10(IP-10)在流行性感冒病毒致肺部炎性病变中的作用,用BALB/c小鼠做动物感染模型,对只感染流感病毒和注射IP-10后感染流感病毒小鼠的肺部炎性反应进行了比较。结果显示,注射IP-10后感染流感病毒小鼠的肺部炎性反应明显重于感染对照组。研究结果表明,IP10对流感病毒造成的肺部炎性病变的严重程度具有重要影响。更多还原

【Abstract】 The aim of this work is to study the role of IP-10 to pulmonary cellular pathogenesis induced by influenza virus.With use of BALB/c mice we give cytokine IP-10 to mice following infection with influenza virus,and compare the inflammation changes in lungs of mice with the lungs of mice only infected with influenza virus.The result shows that IP-10 is closely related to the process and the severity of pneumonia.更多还原