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乙型脑炎减毒活疫苗37℃孵放一周后不同时间的滴度测定
The virus titre detection after incubating JEV at 37℃ for one week
【摘要】 为了了解乙型脑炎减毒活疫苗(简称JEV)的热稳定性,将乙型脑炎减毒活疫苗在37℃孵放一周后2~8℃保存于不同时间进行病毒滴度检测。结果显示,疫苗在37℃孵放一周后2~8℃保存2个月内进行测定,滴度无明显下降趋势。在乙型脑炎减毒活疫苗的热稳定性检测中,37℃孵放一周后2~8℃保存,可在2个月内进行检测,对其热稳定性检测无明显影响。
【Abstract】 To understand the thermostability of Japanese encephalitis live-attenuated vaccine(JEV),this vaccine was incubated at 37℃ for one week and then place at 2-8℃ for two months.The virus titres of JEV were detected in different time within two months.The results indicated that the virus titers are not showed the obvious reduced trend.The thermostability detection of JEV can be carried out within two months after incubating at 37℃ for one week.
【关键词】 乙型脑炎减毒活疫苗;
病毒滴度;
热稳定性;
【Key words】 Japanese encephalitis vaccine live-attenuated(JEV); Virus titration; Thermostability;
【Key words】 Japanese encephalitis vaccine live-attenuated(JEV); Virus titration; Thermostability;
- 【文献出处】 微生物学免疫学进展 ,Progress in Microbiology and Immunology , 编辑部邮箱 ,2009年01期
- 【分类号】R186
- 【被引频次】2
- 【下载频次】140