【摘要】 目的了解贵州省镇宁县布依族、苗族、汉族中老年人幽门螺杆菌(H.pylori)感染状况,探讨与感染有关的流行病学因素。方法采用金标免疫斑点法对镇宁县布依族、苗族、汉族地区592例中老年人自然人群进行血清抗H.pylori-IgG、抗H.pylori-IgM检测。采用问卷方式了解受检者背景资料、生活习惯、健康状况和社会经济卫生状况。应用SPSS14.0统计软件对数据进行处理。结果经过多因素逻辑回归最后筛选出文化程度、人均月收入、生吃大蒜、家居卫生条件、消化道症状、饮用水源、饮水习惯和生吃蔬菜等为H.pylori感染的重要相关流行因素。不同民族、性别、年龄感染率无差异。文化程度、人均月收入、家居卫生条件、经常生吃大蒜、饮茶与IgG阳性率呈负相关;消化道症状、饮用河水井水、生水和生吃蔬菜与IgG阳性率呈正相关。家居条件、生吃大蒜与IgM阳性率呈负相关;消化道症状、生吃蔬菜、饮用河水井水、生水与IgM阳性率呈正相关。结论贵州省镇宁县布依族、苗族、汉族地区是H.pylori感染的高发区。增强自我防护意识,养成良好卫生习惯,提高物质生活水平,改善环境、家庭卫生条件,是个人预防幽门螺杆菌感染的有效方法。更多还原

【Abstract】 Objective To investigate the situation of Helicobacter pylori(H.pylori) infection in Zhenning county of Guizhou province,and to discuss susceptible factors about it.Methods The H.pylori-IgG and H.pylori-IgM were examined in serum samples collected from 592 healthy participants,by DOT-IMMUNOGOLD assay.Questionnaires for knowing their individual information associated with H.pylori infection were obtained from each participant.All data were analyzed with SPSS software.Results The important epidemic factors were concluded as educational level,economic condition,living sanitary condition,gastroenterological symptom,water sources,drinking habit and whether consuming raw vegetables or raw garlic.There was no significant difference on the H.pylori positive rate between different nationalities,sex and age of buyi and miao.The positive rate of IgG of people was negative correlated to educational status,incomings,habitat conditions,garlic and tea intakes;while it was positive correlated to symptom of digestive tract,drinking unboiled water,and improper eating habits.The positive rate of IgM was negative correlated to habitat conditions and eating raw garlic,and was positive correlated to symptom of digestive tract,drinking unboiled water,and improper eating habits.Conclusion Zhenning district is one of the highest H.pylori prevalent areas in China.To prevent us from H.pylori infection,it is necessary to improve our knowledge of prevention disease,develop proper living habits and increase living level and sanitary conditions.更多还原