【摘要】 目的探讨精浆锌(Zn2+)和前列腺特异性抗原(PSA)与精液液化及精子活力的关系。方法筛选精液液化异常患者(异常组)和精液液化正常男性(正常组)各30例,精液常规分析后提取精浆,-20℃保存。采用原子吸收光谱法测定精浆Zn2+含量,ELISA法测定精浆PSA含量,对比分析两组测定结果。结果异常组精浆Zn2+、PSA含量均明显低于正常组。异常组精浆Zn2+平均含量为(82.50±0.72)μg/ml,正常组为(120.43±0.52)μg/ml,两者差异有统计学意义(P<0.01)。异常组精浆PSA平均含量为(0.68±0.14)mg/ml,正常组为(1.21±0.21)mg/ml,两者差异有统计学意义(P<0.05)。异常组精子活力较正常组低(P<0.05)。结论精浆中Zn2+及PSA含量均偏低致精液液化异常并影响精子活力。更多还原

【Abstract】 Objective To investigate the levels of seminal zinc and prostate specific antigen in abnormal liquefaction sperm and their relationship with spermatozoa motility.Methods Thirty cases of abnormal liquefaction sperm(abnormal group)and 30 cases of normal semen liquefaction(normal group)were selected.The semens were analyzed by the CASA,and the seminal plasma was separated and preserved at-20℃.The levels of seminal zinc were measured by atomic absorption spectrometry.The levels of PSA in seminal plasma were detected by ELISA.Results Zn2+ and PSA levels in abnormal group were significantly lower than in normal group(P<0.05).The levels of seminal Zn2+ in abnormal group and normal group were(82.50±0.72)and(120.43±0.52) μg/ml respectively,with the difference being significant between two group(P<0.05).The levels of seminal PSA in abnormal group and normal group were(0.68±0.14) and(1.21±0.21) mg/ml respectively,with the difference being significant between two groups(P<0.05).Sperm motility in abnormal group was lower than in normal group(P<0.05).Conclusion The levels of seminal Zn2+ and PSA in the semens with abnormal liquefaction is low,which resulting in abnormal liquefaction sperm and inhibiting the sperm motility.更多还原