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盐酸小檗碱凝胶剂处方的优选
Prescription screening of berberine hydrochloride hydrogel
【摘要】 优化盐酸小檗碱凝胶剂制备工艺处方。采用正交实验法,对HPMC浓度、PEG400用量和甘油用量三因素进行考查,测定药物溶出度。盐酸小檗碱凝胶剂最佳处方为:盐酸小檗碱0.5,HPMC2.0,PEG4001.0,甘油4.0,亚硫酸氢钠0.1。
【Abstract】 To filterate prescriptons of the Berberine Hydrochloride hydrogel.Orthogonal experimental design the dosage of PEG400、Glycerol and consistency of HPMC in the prescriptions,and toget the releasing degree of effectivedrug. Thebestprescription is:Berberine hydrochloride 0.5, HPMC 2.0, PEG400 1.0, Glycerol 4.0, hydrosulfite of sodium 0.1.
- 【文献出处】 天津化工 ,Tianjin Chemical Industry , 编辑部邮箱 ,2009年01期
- 【分类号】TQ461
- 【被引频次】2
- 【下载频次】301