【摘要】 目的对比研究低中度和高度近视两组准分子激光原位角膜磨镶术(LASIK)手术前后客观视力、像差、对比敏感度、眩光敏感度的差别,以综合评价术前屈光度对LASIK术后视觉质量的影响。方法对行LASIK术的66例(132眼)按等效屈光度(SE)分为两组:低中度近视组(68眼),SE<-6.00 D;高度近视组(64眼),SE≥-6.00 D。采用ARK-10000波前像差分析仪和带眩光光源的CSV-1000E眩光敏感度测量仪分别测量术前和术后1周,1、3个月的客观视力、像差、对比敏感度和眩光敏感度并进行两组间比较。结果(1)术前术后各期最佳矫正视力低中度近视组均优于高度近视组(均P<0.01)。(2)术前与术后各期(1周,1、3个月)比较总体像差高度近视组均高于低中度近视组(P<0.01,P<0.01,P<0.05,P<0.01),各高阶像差成分中,术前两组无明显差异(P>0.05);术后3个月内彗差、球差高度近视组高于低中度近视组(P<0.01),而三叶草像差、四叶草像差和高阶散光两组间无明显差异(P>0.05)。(3)术前,两组在空间高频区(18.0 c.d-1)对比敏感度有差异,低中度近视组优于高度近视组(P<0.05);术后早期两组对比敏感度均下降,随时间逐渐恢复,其中高度近视组下降更明显恢复也较慢。至术后3个月两组均恢复至术前水平,高频区对比敏感度低中度近视组仍优于高度近视组(P<0.05)。(4)术前,两组在12.0 c.d-1频率上眩光敏感度有差异,低中度近视组优于高度近视组(P<0.05)。术后早期两组眩光敏感度均下降,随时间逐渐恢复;其中高度近视组下降更明显,恢复较慢。至术后3个月两组均恢复至术前水平,两组间各频率眩光敏感度均无明显差异(P>0.05)。结论(1)近视LASIK术后早期的视觉质量低中度近视组优于高度近视组;(2)术后视觉质量的恢复高度近视组慢于低中度近视组;(3)两组术后中晚期均拥有良好的视觉质量。更多还原

【Abstract】 Objective To evaluate the effect of diopter correction on visual function after laser in situ keratomileusis(LASIK) by comparing moderate myopia with high myopia.Method Sixty-six patients 132 eyes were divided into 2 groups based on spherical equivalent:moderate myopia group(﹤-6.00 D,68 eyes) and high myopia group(≥-6.00 D,64 eyes).Visual activity,aberration,contrast sensitivity and glare sensitivity were measured by phoropter,ARK-10000 wavefront analyzer,and CSV-1000E with glare respectively.Results(1)Best spectacle-correct visual acuity was better in moderate myopia group before and after LASIK(P<0.01).(2)Total aberration was higher in high myopia group before and after LASIK(P<0.01,P<0.01,P<0.05,P<0.01).No significant difference in higher order aberration was found between 2 groups before LASIK(P>0.05).After LASIK,total coma and total spherical aberration were higher in high myopia group(P<0.01)while total trefoil,total 4foil and high astigmatism didn’t show significant differences between 2 groups(P>0.05).(3)Contrast sensitivity was better in moderate myopia group at spatial frequency 18.0 c·d-1 before LASIK(P<0.05).After LASIK,contrast sensitivity in both groups decreased with high myopia group decreased to the greater extent.Within 3 months,they returned gradually to pre-LASIK levels;but high myopia group recovered more slowly.(4)Glare sensitivity was better in moderate myopia group at spatial frequency 12.0 c·d-1 before LASIK(P<0.05).After LASIK,glare sensitivity in both groups decreased with high myopia group decreased more.After 3 months,they both returned to pre-LASIK levels.And no significant difference in glare sensitivity was seen between 2 groups at any frequency(P>0.05).Conclusions(1)The disturbance of visual function after LASIK is more prevalent in patients with high myopia.(2)The visual function recovery occurs slower in patients with high myopia.(3)After a period of recovery time,visual function is found good in both groups.更多还原