【摘要】 目的了解安仁县主要恶性肿瘤死亡流行特征,综合评估其对人群寿命年损失的影响,为开展肿瘤防治工作提供科学依据。方法按照全国第三次死因回顾性调查方案,对2004-2005年安仁县主要死因进行回顾性调查,采用图表结合的方法,绘制以平均潜在减寿年数(AYPLL)为y轴,死亡人数为x轴的潜在减寿年数(YPLL)面积图及其它相关图表分析不同恶性肿瘤对寿命年损失的影响。结果2004-2005年,安仁县恶性肿瘤死亡率为134.12/10万(标化率为98.26/10万),列全死因第二位;YPLL前5位的恶性肿瘤依次为:肝癌、胃癌、白血病、肺癌及脑恶性肿瘤;AYPLL前5位则依次为:白血病、鼻咽癌、脑恶性肿瘤、宫颈癌及肝癌;不同年龄组恶性肿瘤死亡的潜在减寿年数率(YPLL率)先升后降,且男性高于女性(20~岁组除外)。结论YPLL面积图对分析肿瘤的疾病负担的特点方便、直观;肝癌和白血病对安仁县寿命年损失危害最大,其病死人数多,且年龄结构较轻;胃癌和肺癌造成的"早亡"人数较多;而因脑恶性肿瘤"早亡"的人群人数相对较少,但年龄结构年轻。更多还原

【Abstract】 Objective To investigate the epidemiological characteristics of malignant tumor deaths in the registered population of Anren County in Hunan Province, to assess the impact for "premature deaths" from malignant tumors,and to provide the scientific evidence for control and prevention of malignant tumors. Methods A retrospective survey of death caused by malignant tumors from 2004 to 2005 was performed in the registered population of Anren County,which was based on the protocol of the third national retrospective survey of death.With a graphic method,the impact of different malignant tumors on years of life lost was analyzed by drawing an area chart of the potential years of life lost(YPLL) with an average of the potential years of life lost(AYPLL) for the y-axis and the death toll for the x-axis. Results The mortality rate of malignant tumors was 134.12/100,000,with the standardized mortality rate of 98.26/100,000 in Anren County from 2004 to 2005.Malignant tumor death was the second common cause of death.The top five cancers ranked by YPLL were liver cancer,gastric cancer,leukemia,lung cancer,and brain malignant tumor;and by "average years of potential life lost"(AYPLL) were leukemia,nasopharyngeal cancer,brain malignant tumor,cervical cancer,and liver cancer.In different age groups,the rate of YPLL increased firstly and decreased afterwards and fluctuations existed.YPLL rates of men in each age group were higher than those of women,but the age group of 20～30 years was excluded. Conclusions It is convenient and visual for using YPLL area chart to analyze the disease burden from cancers.Liver cancer and leukemia are the main causes of the life lost in Anren County,and moreover,with a larger number of young deaths.Gastric cancer and lung cancer cause a large number of premature deaths.The premature deaths from brain malignant tumor are relatively fewer,but the age of them is younger.更多还原