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女性冠心病临床特征研究进展

The clinical research of gender differnces for women with coronary heart disease.

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【作者】 周志文徐亚伟胡大一

【Author】 ZHOU Zhi-wen,XU Ya-wei,HU Da-yi.Shanghai Tenth People’s Hospital Affiliated Tongji University,Shanghai 200072,China

【机构】 上海同济大学附属第十人民医院心内科上海同济大学心肺血管中心

【摘要】 冠心病是影响女性身体健康和死亡的头号病因。由于性别、生理和社会环境的不同,与男性相比,女性冠心病在危险因素、临床表现及其治疗预后上均有着不同程度的差异。当前女性冠心病主要有如下特点:社会重视程度不足;危险因素较特殊;心肌缺血症状不典型;就医时危险因素多和病情重;治疗不够积极;病死率高。因此,当前有必要加强对女性冠心病的研究和诊治工作,以全面提高女性冠心病的防治水平。

【Abstract】 Coronary heart disease(CHD) is the leading cause of death among women worldwide.Recent technological advances in cardiovascular diagnosis and treatment have not led to significant declines in mortality for women with CHD when compared to the dramatic declines for men.Owing to the gender differences of physiology and social circumstances,women with CHD may have different manifestations as compared to men with CHD.Recently,research has shown that women with CHD had mainly the following characteristics:special risk factors,atypical ischemia symptoms,multiple risk factors and comorbidities at initial physician consultation,higher under-treatment rate and higher mortality rate.At the same time,most CHD researches have paid little attention to women.Therefore,the current CHD guidelines may not be completely suitable for women.In order to improve the prevention and treatment of CHD in women,we advocate to enhance research and clinical work for women with CHD. Abstract:Summ ary:Coronary heart d isease(CHD) is the lead ing cause of death among wom en worldw ide.Recent technological advances in card iovascu lar d iagnosis and treatm ent have not led to sign ificant dec lines in mortality for wom en w ith CHD when compared to the dram atic dec lines form en.Ow ing to the gender d ifferences of physiology and soc ial c ircum stances,wom en w ith CHD m ay have d ifferent m an ifestations as compared to m en w ith CHD.Recently,research has shown that wom en w ith CHD had m ain ly the follow ing characteristics: spec ial risk factors,atyp ical ischem ia symptom s,mu ltip le risk factors and comorb id ities at in itial physic ian consu ltation,h igher under-treatm ent rate and h igher mortality rate.At the sam e tim e,most CHD researches have paid little attention to wom en.Therefore,the current CHD gu idelines m ay not be comp letely su itab le forwom en.In order to improve the prevention and treatm ent of CHD in wom en,we advocate to enhance research and c lin ical work for wom en w ith CHD.

  • 【文献出处】 中国实用内科杂志 ,Chinese Journal of Practical Internal Medicine , 编辑部邮箱 ,2009年08期
  • 【分类号】R541.4
  • 【被引频次】45
  • 【下载频次】822
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