【摘要】 系统性红斑狼疮(systemic lupus erythematosus,SLE)的治疗近年来取得了长足的进步,尤其是各类新型免疫抑制剂的临床应用,进一步提高了患者的缓解率和生活质量。然而,部分出现严重并发症的重症狼疮患者,仍需要血浆净化治疗。随着血浆净化技术的迅速发展,其吸附抗体的效率和特异性均大幅提高,在一些威胁生命的重症狼疮急性期的治疗中起了重要作用,本文就血浆净化各类新技术以及在SLE临床应用的相关情况做一综述。更多还原

【Abstract】 Recently,considerable progress has been made in the treatment of systemic lupus erythematosus(SLE),especially in the clinical use of new immunosuppressive agents,which leads to improved remission rate and life quality.However,plasmapheresis still shows to be necessary in severe lupus with serious complications.With the development of plasmapheresis technology,the efficiency and specificity of antibody adsorption being improved significantly,it played an important role in the treatment of acute stage life-threaten lupus.Here we intend to make a review on the relative improvement of plasmapheresis technology and its clinical use.更多还原