【摘要】 目的:了解腮腺切除术中面神经外血管系破坏与否对面神经核的影响。方法:选用健康家兔,采用同体对照的方法,模拟人腮腺全切术。实验侧于手术显微镜下腮腺全切,解剖面神经,保护面神经外血管系;对照侧镜下完成相同手术,但破坏面神经外血管系。术后2、3、4周分别取面神经核透射电镜下观察其超微结构的病理变化。结果:术后3组动物实验侧面神经核细胞超微结构正常,未见明显变化;对照侧面神经核内线粒体变性,大部分细胞器失去正常结构,随时间延长出现明显病理变化。结论:在腮腺切除术中解剖面神经破坏其外血管系,可导致面神经核细胞超微结构发生明显的病理变化,这可能是腮腺切除术后患者发生面瘫的原因之一。更多还原

【Abstract】 Objective:To observe the effect of parotidectomy and dissecting facial nerve on facial nucleus.Methods:Healthy rabbits were used for parotidectomy.Capillary net on the facial nerve was protected on the experimented side when excising parotid glands and dissecting facial nerve under surgical microscope.The same operation was performed on the control side,but the capillary net was damaged.The facial nucleus in brain was taken out and observed under transmission electron microscope at 2,3 and 4 weeks after parotidectomy.Results:On the experimental side,the ultrastructure of facial nucleus of three groups were normal after operation,while pathological changes were easily observed on the control side.Conclusion:Capillary net damage can lead to obvious ultrastructural changes of facial nucleus and may be a reason for facial paralysis after parotidectomy.更多还原