【摘要】 目的:初步探讨牙周炎与慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)的关系。方法:选择符合纳入标准的受试者498名,其中轻度、中度及重度牙周炎组分别为77人(15.5%),143人(28.7%),278人(55.8%)。牙周检查包括:牙周探诊深度(probing depth,PD),牙周附着丧失(attachment loss,AL),龈沟出血指数(sulcus bleeding index,SBI),菌斑指数(plaque index,PLI),牙槽骨吸收水平。通过支气管舒张剂吸入试验测定受试者肺功能水平。结果:COPD组的AL、PLI及牙槽骨吸收水平显著高于非COPD组。其中不同程度牙周炎组之间第1秒用力呼气容积占预计值的百分比(FEV1%预计值)(F=3.59,P=0.028)及第1秒用力呼气容积占用力肺活量的百分比(FEV1/FVC)(F=4.84,P=0.008)的差异有统计学意义。支气管舒张剂后"FEV1%预计值"及"FEV1/FVC"与牙周检查指标(AL,PLI,牙槽骨吸收水平)之间均有显著负相关关系。结论:COPD与牙周检查指标(AL,PLI,牙槽骨吸收水平)之间存在相关性。更多还原

【Abstract】 Objective:To explore the relationship between Chronic Obstructive Pulmonary Disease(COPD) and periodontitis.Methods:498 subjects were recruited in this study and were divided into three groups:mild periodontitis group(77,15.5%),moderate periodontitis group(143,28.7%),and severe periodontitis group(278,55.8%).Clinical examination indexes included probing depth(PD),attachment loss(AL),sulcus bleeding index(SBI),plaque index(PLI) and the level of the alveolar resorption.Lung function of each subjects were also examined.Results:The levels of AL,PLI and alveolar resorption in COPD group were higher than non-COPD group.Significant differences of "FEV1% pre"(F=3.59,P=0.028) and "FEV1/FVC"(F=4.84,P=0.008) were found among different degrees of periodontitis.Negative relationship was found between the level of "FEV1% pre" and the periodontal index(AL,PLI,alveolar resorption),and the same relationship was found for "FEV1/FVC".Conclusion:Correlation is found between COPD and the periodontitis index(AL,PLI,alveolar resorption).更多还原