【摘要】 目的:探讨持续性不卧床腹膜透析(CAPD)患者残肾功能,腹膜透析的充分性和腹膜转运特性对钙磷代谢的影响。方法:连续不卧床腹膜透析患者43例,透析时间3.5～34个月,透析剂量6～8L/d。用腹膜平衡试验测定腹膜转运功能。以残肾GRF>2ml/min为有残余肾功能的界线。所有患者以尿素清除指数(kt/v)≥1.7和肌酐清除率(Ccr)≥50L/周.173m2为透析充分的最低标准。结果:没有残肾功能的患者血磷和钙磷乘积较有残肾功能者明显升高。结论:CAPD患者普遍存在钙磷代谢紊乱,以血磷和钙磷乘积升高较明显,残存肾功能对血磷的清除起着重要的作用。更多还原

【Abstract】 Objective:To investigate the influence of residual renal function,abundance of dialysis and peritoneal membrane transport capacity on the calcium and phosphorus metabolism in continued ambulatory peritoneal dialysis patients (CAPD). Methods:Forty three patients undergoing CAPD from 3.5～34 months with dialysis dosage 6～8L/d were researched peritoneal function characteristics using the peritoneal equilibration test(PET).The residual renal function of the CAPD patients was set a target minimum of 2ml/min.The most minimal standard about the abundance of dialysis was that (kt/v) ≥1.7 and Ccr >50L/week.173m2 to all of the subjects in this test. Results:The patients who had not owned residual renal function had significant elevated serum phosphorus level and value of (CA2+)*(P2+)(P<0.05). Conclusion:Disorders of calcium and phosphorus metabolism,especially hyper serum phosphorus and higher calcium-phosphorus product are common in CAPD patients. The residual renal function plays an important role in the clearance of serum phosphorus.更多还原