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一种新型基因载体——SucPG络合物的研究进展
The Research Progress of a Novel Gene Vector——SucPG-complex
【摘要】 简要介绍了一种新型基因载体——SucPG络合物的研究进展,它由连有转铁蛋白的SucPG(琥珀酰多聚甘油)修饰的脂质体与lipoplex络合形成,具有较高的转染活性,抗血清性和毒性低等一系列的优点。
【Abstract】 The research of gene vectors has received growing attention in recent years.In this paper,the research progress of a novel gene vector which is called SucPG-complex was introduced briefly.The SucPG-complex which was prepared by complexation of the transferrin-bearing SucPG-modified liposomes with the lipoplex,features many advantages such as high transfection activity,serum-resistance,low cytotoxicity.
【关键词】 基因载体;
SucPG络合物;
转染活性;
抗血清性;
毒性;
【Key words】 Gene vector SucPG-complex Transfection activity Serum-resistance Cytotoxicity;
【Key words】 Gene vector SucPG-complex Transfection activity Serum-resistance Cytotoxicity;
【基金】 国家自然科学基金资助项目(20876023)
- 【文献出处】 生物技术通报 ,Biotechnology Bulletin , 编辑部邮箱 ,2009年02期
- 【分类号】Q78
- 【被引频次】1
- 【下载频次】112