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闪光视觉诱发电位单次提取的自参考自相关自适应干扰对消技术

On the Auto-Reference,Auto-Correlation and Adaptive Interference Cancellation Theories and Techniques for Single Extracting Flash Visual Evoked Potential

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【作者】 王志芳谢正祥钟雪飞王颖李虹刘玉红杨娟张婧黄祖春

【Author】 Wang Zhifang1 Xie Zhengxiang2 Zhong Xuefei2 Wang Ying2 Li Hong2Liu Yuhong2 Yang Juan3 Zhang Jing3 Huang Zuchun31(Chongqing Medical Instrument Quality Inspection Center,Chongqing 401121,China)2(Department of Biomedical Engineering,Chongqing Medical University,Chongqing 400016,China)3(Department of Neurology,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)

【机构】 重庆医疗器械质量检验中心重庆医科大学生物医学工程研究室重庆医科大学附属第一医院神经科

【摘要】 在分析传统的诱发电位提取的叠加平均理论缺陷的基础上,根据对自发脑电信号特性的认识和诱发电位提取的特定环境,提出了闪光视觉诱发电位(FVEP)单次提取的自参考自相关自适应干扰对消理论和技术(AAA-ICT)。该技术用求诱发脑电信号与参考信号的逐点滑动相关的方法,获得与诱发脑电信号有最大相关的参考信号段,用最小二乘原理(LSM)求取诱发脑电信号中有最大相关的参考信号段的对消因子W,然后进行干扰对消以获得单次提取的FVEP。用该技术能够有效地提取FVEP信号,并能获得单个受试者FVEP的变异性。

【Abstract】 On the basis of analyzing the defects in traditional averaging theory for extracting evoked potential(EP),and by realizing the characteristic of spontaneous electroencephalo-signal (S-EES) as well as the special environment for extracting EP,we propose an auto-reference,auto-correlation,adaptive interference cancellation (AAA-ICT) for use in the single trial of flash visual evoked potential (FVEP). Firstly,the segment of reference signal,which has the best correlation with evoked electroencephalo-signal (E-EES),was obtained using the method for calculating the sliding correlation point by point between E-EES and reference signal; then,the cancellation factor between E-EES and the most correlative reference signal segment was derived by the least square method; at last,the single trial of FVEP was acquired by interference cancellation. By this method,FVEP can be extracted perfectly and the FVEP variability of individual inter-stimulation can be obtained.

【基金】 国家自然科学基金资助项目(30670536)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2009年05期
  • 【分类号】R741
  • 【被引频次】1
  • 【下载频次】83
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