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新型膳食纤维脂蛋白吸附剂的研制

A Preparation and Study of a Novel Amphiphilic Lipoprotein Adsorbent with Dietary Fiber as Carrier

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【作者】 王睿睿方波杨光夏春岚赵辉刘丽荣黄丽

【Author】 Wang Ruirui Fang Bo Yang Guang Xia Chunlan Zhao Hui Liu Lirong Huang Li(Research Center of Chemical Engineering in East China University of Sci.&Tech.,Shanghai 200237,China)

【机构】 华东理工大学化学工程研究所

【摘要】 研究以花生壳膳食纤维为载体,以十二胺和氯磺酸为原料,引入疏水基团和亲水基团的双亲型低密度脂蛋白吸附剂的制备工艺,探讨反应时间、反应温度对吸附能力的影响。结果表明,该吸附剂可使血浆总胆固醇吸附率达到40.8%,低密度脂蛋白胆固醇吸附率达到50.8%,高密度脂蛋白胆固醇的吸附率为23.6%。该吸附剂对低密度脂蛋白具有良好的吸附选择性。

【Abstract】 The preparation of a novel amphiphilic dietary fiber LDL adsorbent with sulfonic group and laurylamine group was studied.The effects of reaction time and reaction temperature on the adsorption rate were studied.The results show that the adsorption rates for the removal of Total cholesterol(TC),Low-density lipoprotein cholesterol(LDL-C) and High-density lipoprotein cholesterol(HDL-C) are 40.8%,50.8% and 23.6%,respectively.The amphiphilic adsorbent has better selectivity in removing LDL-C.

  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2009年03期
  • 【分类号】TQ424
  • 【被引频次】4
  • 【下载频次】152
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