【摘要】 目的:探索防治放射性颌骨骨髓炎的有效措施。方法:通过对37例放射性颌骨骨髓炎临床病例资料回顾性的总结,对其年龄、性别、病种分类、放射剂量、临床表现、发生因素及诊治方法进行研究分析。结果:1.本组病例放疗后均出现严重的口干症,以及龋病与牙周病。2.鼻咽癌患者放疗后骨髓炎病变多发生在上颌骨后牙区及下颌骨升支区,并伴有严重的张口受限。3.口腔癌患者放疗后的病变区多发生在下颌骨体部,出现严重的牙周病及根尖周病。结论:放疗前后加强口腔健康维护,积极防治牙体牙周疾病,增加唾液分泌措施的应用,坚持张口训练等,可降低放射性颌骨骨髓炎的发生或病变程度。手术清除死骨和病灶牙是放射性颌骨骨髓炎治疗的最有效措施。而精确放疗技术的应用可大大降低放射治疗并发症的发生。更多还原

【Abstract】 Objective:To investigate effective methods for preventing treatment Osteoradionecrosis of jaws.Method: 37 cases of Osteoradionecrosis of jaws were reviewed,and it is analyzed on the patients’age,gender,and entity classification of disease,etiological factor,clinical manifestation,and radiation dose in treatment,and early diagnosis treatment methods in details.Result: 1.Severe xerostomia,dental caries,periodontal disease appear in all patients after radiotherapy.2 For patients with cancer of pharynx,postradiotherapy osteomyelitis mostly appear in posterior teeth area in maxillary bone and ascending branch of mandibular bone,and patients bear limitation of mouth opening.3 For patients with carcinoma of mouth,postradiotherapy osteomyelitis mostly appear in mandible body,and severe periodontal disease,periapical disease occur simultaneously.Conclusion: These methods are effective to decrease the incidence rate and severity of Osteoradionecrosis of jaws during and after radiotherapy,including enhancement oral health maintenance,prevention treatment for odontal and periodontal disease,enhance salivary secretion and practising open mouth movement.But the most effective measure is eliminates the sequestrum and the focus of involved teeth by surgical operation.Applying precise radiotherapy technology extremely reduce the disease incidence of complication after radiotherapy.更多还原