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27个群体7个Y-STR基因座多态性的聚类分析

The Genetic Relationship of 7 Y-STR loci in 27 Populations

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【作者】 朱永生霍正浩赖江华李生斌党洁金彩霞彭亮梁青

【Author】 ZHU Yong-sheng1,HUO Zheng-hao1,LAI Jiang-hua2,LI Sheng-bin2,DANG Jie1,JIN Cai-xia1,PENG Liang1,IANG Qing1(1 Key Laboratory of Reporoduction and Genetics in Ningxia,Department of Medical Genetics and cell biology,NingXia Medical College,Yinchuan,750004,China;2 Key Laboratory of Forensic Science,Ministry of Health,Xi’ an Jiaotong University College of Medicine;Xi’an 710061,China)

【机构】 宁夏生殖与遗传重点实验室宁夏医学院医学遗传学与细胞生物学教研室西安交通大学医学院卫生部法医学重点实验室

【摘要】 目的:选择具有高度多态性与稳定性的7个Y-STR位点,分析27个群体遗传关系。方法:应用Y-STR复合扩增方法,获得150名宁夏回族个体DYS19、DYS389I、DYS389Ⅱ、DYS390、DYS391、DYS392、DYS3937个基因座等位基因频率。收集国内外26个群体这7个基因座基因频率的数据。结果:应用这7个Y染色体STR的多态性研究结果显示:国内群体与朝鲜、韩国、日本的遗传关系较近,与几内亚、莫桑比克的遗传关系较远。结论:27个不同群体这7个Y-STR基因座多态性有明显的种族与地域差异,与三大人种的分类基本一致。

【Abstract】 Objective:To study the genetic relationship of 7 Y chromosomal short tandem repeat gene loci(abbreviated as 7 Y-STR gene loci) in 27 populations.Methods:The frequency of 7 Y-STR loci alleles(DYS19,DYS389,DYS389Ⅱ,DYS390,DYS391,DYS392 and DYS393) from 150 unrelated individuals from Ningxia was obtained by multiplex amplification.Internal and external ge-netic data of 7 Y-STR loci on 26 populations were collected.Results:The result showed that the populations in China,Korea,Republic of korea,Japan were close like each other,while the populations in Guinea and Mozambique were far from the other groups.Conclusion:It is indicated that the Y-STR gene frequency distribution in 27 populations has identified differentiation in race and dialect,and it is basi-cally identical with the classification of 3 human races.

【关键词】 Y-STR复合扩增聚类分析群体
【Key words】 Y-STRMultiplex amplificationPylogenetic treePopulation
【基金】 宁夏自然科学基金(NZ0659)
  • 【文献出处】 现代生物医学进展 ,Progress in Modern Biomedicine , 编辑部邮箱 ,2009年02期
  • 【分类号】R394
  • 【被引频次】5
  • 【下载频次】307
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