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黄芪多糖咀嚼片降血脂人体试食试验研究

Hypolipidemic Effect of Astragalus Polysaccharide Mastication Tablet on Human Body

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【作者】 昭日格图娜日苏博日吉汗格日勒图韩景芬领小吐尔孙拜克

【Author】 ZHAORIGETU ,NARISU,BORIJIHANGERILETU,HAN Jing-fen,LING Xiao,TUERSUNBARKE (Institute of Macromolecular Chemistry and Mongolian Medicine,Inner Mongolia University,Huhhot 010021,China)

【机构】 内蒙古大学高分子化学及蒙药研究所

【摘要】 选择101例符合纳入标准的单纯血脂异常志愿者(其中男67人,女34人)作为受试对象,观察黄芪多糖对人体的降血脂作用。受试者被随机分为安慰剂组和试食组,采用双盲的方法给予黄芪多糖咀嚼片。受试者不改变生活饮食习惯,每日食用黄芪多糖咀嚼片3g,连续45d,受试者在食用前和食用2个月后分别采静脉血,测定各项生化指标,观察功能性指标(总胆固醇、甘油三酯、高密度脂蛋白)的有效率及降血脂总有效率。结果显示,黄芪多糖对人体具有辅助降低血清总胆固醇的功能,对受试者健康无影响。

【Abstract】 The effects of Astragalus polysaccharide on serum lipid profile in 101 volunteers only with dyslipidemia (67 men and 34 women) were studied. The subjects were randomized into placebo control group and test group in a double-blind way administered with 3 g of Astragalus polysaccharide mastication tablet orally per day for 45 days. The venous blood was collected before and two months after administration of Astragalus polysaccharide,and the biochemical indexes were assayed and the reduction or increase efficiency of functional indexes (i.e.,total cholesterol,triglyceride,and high density lipoprotein) and the total hypolipidemic efficiency were measured. The experimental results demonstrate that Astragalus polysaccharide has auxiliary effect on reducing serum total cholesterol without any adverse effects on subjects’health.

【基金】 国家自然科学基金项目(30160103)
  • 【分类号】R285
  • 【被引频次】22
  • 【下载频次】554
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