【摘要】 目的探讨肺炎衣原体(CPn)、人类巨细胞病毒(HCMV)、幽门螺杆菌(Hp)在人体的感染与冠心病的相关性。方法随机选取2006年1月～2007年12月住院的冠心病患者92例作为冠心病组,同时随机选择同期健康体检者92例作为健康对照组。用酶联免疫吸附试验检测CPn、HC-MV、Hp三种微生物的感染状况。结果冠心病组CPn-IgM、IgA,HCMV-IgM、IgG情况与健康对照组比较有显著性差异(P<0.05);冠心病组CPn-IgG,Hp-IgM、IgG与健康对照组比较无显著性差异。结论CPn、HCMV长期反复慢性混合感染与冠心病关系密切,是区别于高脂血症、高血压、吸烟、糖尿病的独立危险因素,对冠心病的诊断治疗有积极意义。更多还原

【Abstract】 Objective To explore the relativity of infection of chlamydia pneumoniae(CPn),human cytomegalo virus(HCMV)and helicobacter pylori(Hp)with coronary heart disease(CHD)and.Methods From January 2006 to December 2007,92 in-patients of CHD were randomized into CHD group and 92 persons who received health examination at the same period were selected in health control group.ELISA method was adopted to detect the infectious conditions of three microorganisms,named CPn,HCMV and Hp.Results Significant differences were obtained in CPn-IgM,IgA,HCMV-IgM and IgG in the comparison between CHD group and health control group(P<0.05).The differences were not significant in CPn-IgG,Hp-IgM and IgG in the comparison of two groups.Conclusion Long-term repeated,chronic and mixed infection of CPn and HCMV is relevant to coronary heart disease,which is the independent risk factor being different from hyperlipidemia,hypertension,smoking and diabetes mellitus and it is positively significant in the diagnosis and treatment of coronary heart disease.更多还原