节点文献
MicroRNA与神经系统重大疾病
Functions of MicroRNA in Nervous System Regulation
【摘要】 目前有研究证实microRNA参与了神经系统生长发育和生理功能的调控,它也与可塑性障碍性疾病、神经系统退行性疾病、神经系统肿瘤、脑血管疾病等重大疾病的发生发展相关.随着microRNA研究领域的发展,一些重大神经系统疾病的相关发病机制将有可能被阐释.
【Abstract】 Many investigations have demonstrated that microRNA (miRNA) is not only involved in the modulation of nerve cell growth and physiological activity, but also responsible for dysfunctions in synaptogenesis or synaptic plasticity, neurodegenerative diseases, tumorgenesis in the nervous system, as well as in cerebrovascular disorders. With the intensive researches in miRNA, it is possible gradually to explain the related pathogenic mechanisms of some major diseases in the nervous system.
【关键词】 microRNA;
神经系统生长发育;
神经系统重大疾病;
【Key words】 microRNA; nerve cell growth; major diseases of nervous system;
【Key words】 microRNA; nerve cell growth; major diseases of nervous system;
【基金】 浙江省自然科学基金(Y2080132);浙江省科技支撑和引导计划(2007C33007);国家自然科学基金(30570582)资助项目~~
- 【文献出处】 生物化学与生物物理进展 ,Progress in Biochemistry and Biophysics , 编辑部邮箱 ,2009年01期
- 【分类号】R741
- 【被引频次】21
- 【下载频次】1501