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表观遗传调节与常见疾病的发生
Epigenetic regulation and human common diseases
【摘要】 近年来发现一些表观遗传调节方式以及表观遗传特征变化与多种疾病相关。表观遗传机制的失调将影响染色质结构和基因表达,导致复杂的综合征、多因素疾病及癌症。文章就几种常见疾病的表观遗传机制研究进展作一综述。
【Abstract】 In the past few years,it has been disclosed that identified epigenetic processes and epigenetic changes are involved in human diseases.Disorders of these processes may influence chromatin structure and gene expression,which may result in complicated syndroms,multiple-factor diseases and cancers.The research progress of epigenetic processes of several diseases is reviewed in this paper.
【关键词】 表观遗传;
癌症;
心血管病;
代谢综合征;
自身免疫病;
【Key words】 epigenetics; cancer; angiocardiopathy; metabolism syndrom; autoimmune diseases;
【Key words】 epigenetics; cancer; angiocardiopathy; metabolism syndrom; autoimmune diseases;
- 【文献出处】 上海交通大学学报(医学版) ,Journal of Shanghai Jiaotong University(Medical Science) , 编辑部邮箱 ,2009年10期
- 【分类号】R394
- 【被引频次】5
- 【下载频次】1247