【摘要】 目的应用国产单向活瓣支架进行可弯曲支气管镜介入肺减容术(BILVR)临床研究,初步探讨支架的放置与取出技术。方法选择2006年5月至2008年3月8例重度肺气肿患者,其中男性7例,女性1例,年龄43～70岁。在全身麻醉下行可弯曲支气管镜支架置入,其中对2例患者行全部或部分取出支架。结果8例患者在单侧上叶支气管段或亚段放置4～6个支架,手术时间为(124.00±63.26)min。术后2h可自行活动,呼吸困难明显减轻。1例患者在术后2d出现非靶区下叶肺炎、1例患者出现慢性阻塞性肺疾病急性发作,均治疗后缓解。其余患者均未出现严重并发症。随访6~24个月,2例部分支架远端出现肺炎,行全身麻醉经纤维支气管镜支架取出术,未出现严重并发症。结论全身麻醉单向活瓣肺减容支架的放置与取出术操作简单,较为安全。更多还原

【Abstract】 Objective To evaluate the technique of implanting and withdrawing the domestic-made stents in the study on clinical application of bronchoscopic interventional lung volume reduction. Methods From May 2006 to March 2008,8 cases with severe emphyseme,male 7,female 1,aged 43 - 70 years,were implanted flexible stents under general anesthesia. Among them total or partial withdrawal were performed in 2 patients. Results Four to six stents per patient were implanted into the obstructed upper-lobe branchial segments unilaterally with operation time (124.00 ± 63.26) min. All patients could walk in 2 hours after operation,their dyspnea relieved obviously. No major life-threatening complications were found. Lower-lobe pneumonia developed in 1 patient and 1 patient occurred acute episode of chronic obstructive pulmonary disease (COPD). Pneumonia occurred in 2 patients during following-up 6 - 24 months. Stents withdrawal were performed in 2 patients due to the distal end pneumonia. Conclusion The technique of stents implantation and withdrawal with one-way value stent lung volume reduction under general anesthesia is convenient and comparatively safe.更多还原