【摘要】 目的:探讨体外受精-胚胎移植(IVF-ET)中宫腔积液产生的原因及其对助孕结局的影响。方法:回顾性分析2006年1月至2007年12月间在我院接受IVF助孕的1963个周期,其中106个周期出现宫腔积液。根据有无输卵管积液和宫腔积液分组,分析宫腔积液患者不育原因、超排卵反应及妊娠率。结果:输卵管积液组宫腔积液发生率为7.7%,无输卵管积液组宫腔积液发生率为4.8%,两组比较差异有统计学意义(P<0.05),两组发生卵巢过度刺激综合征(OHSS)的患者宫腔积液发生率分别为15.2%、9.1%,均高于同组未发生OHSS的患者(P<0.05);输卵管积液组患者出现宫腔积液后临床妊娠率显著下降(P<0.05)。结论:控制性超排卵中输卵管积液和OHSS均增加宫腔积液发生率;除输卵管积液患者外,助孕中出现宫腔积液IVF妊娠率不受影响。更多还原

【Abstract】 Objective:To investigate the mechanisms of endometrial cavity fluid(ECF),and its impact on the pregnancy outcome of IVF.Methods:A retrospective analysis was performed on 1963 IVF cycles involving 106 cycles with ECF during January 2006 to December 2007;the cycles were classified by presence of hydrosalpinx and ECF(detected by ultrasound).The infertility diagnoses,ovarian response and pregnancy rate were compared among the groups.Results:The incidence of ECF in the hydrosalpinx was 7.7% higher than patients without hydrosalpinx 4.8%(P<0.05).The incidence of ECF in OHSS patients was higher than patients without OHSS(P<0.05).Pregnancy rate was lower in the hydrosalpinx patients in the presence of ECF in comparison with all other patients(P<0.05).Conclusions:Hydrosalpinx and ovary high response,OHSS may increase the incidence of ECF.Endometrial cavity fluid during ovarian stimulation in IVF cycles impairs the outcome of hydrosalpinx patients,but not other patients.更多还原