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女性高血压人群血脂水平与缺血性卒中的相关性

Correlation between the level of blood lipids and the risk of ischemic strokein women with hypertension

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【作者】 杨红梅张心刚郑黎强孙兆青孙英贤

【Author】 YANG Hong-mei1,ZHANG Xin-gang,ZHENG Li-qiang,SUN Zhao-qing,SUN Ying-xian(1The First Hospital Affiliated to China Medical University,Shenyang 110001,P.R.China)

【机构】 中国医科大学附属第一医院中国医科大学附属第二医院

【摘要】 目的探讨女性高血压人群血脂水平与缺血性卒中的关系。方法对3 607例女性原发性高血压病患者进行流行病学调查和实验室检查,通过Logistic回归获得各类血脂水平对缺血性卒中的风险率及95%可信区间(CI)。结果调整各种混杂因素后,非高密度脂蛋白胆固醇(non-HDL-C)和总胆固醇与高密度脂蛋白胆固醇比率(TC/HDL-C)与缺血性卒中显著相关,OR分别为1.253(95%C,I 1.039~1.512)和1.594(95%CI,1.267~2.006)。结论non-HDL和TC/HDL-C是女性高血压人群缺血性卒中独立的预测因子。

【Abstract】 Objective To evaluate the correlation between the level of blood lipids and the risk of ischemic stroke in women with hypertension.Methods An epidemiological studies and laboratory assess to a resident group of 3 607 women with hypertension were conducted.Odds ratios(OR) and 95% confidence intervals(CI) for ischemic stroke were calculated by using logistic regression.Results After adjusting for independent variables,non-HDL cholesterol(non-HDL-C) and TC: HDL-C ratio had a significant association with ischemic stroke.The adjusted OR and CI were 1.253(95%CI,1.039-1.512) and 1.594(95%CI,1.267-2.006) respectively.Conclusions Non-HDL-C and TC: HDL-C ratio are the independent risk factor for ischemic stroke in women.

【关键词】 胆固醇血脂脑卒中高血压
【Key words】 cholesterollipidsstrokehypertension
【基金】 辽宁省科技攻关重点项目(2003225003)
  • 【文献出处】 山东医药 ,Shandong Medical Journal , 编辑部邮箱 ,2009年47期
  • 【分类号】R544.1
  • 【被引频次】2
  • 【下载频次】79
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