【摘要】 目的观察慢性阻塞性肺疾病(COPD)稳定期肺功能与生活质量的关系。方法采用美国波士顿健康研究所研制的简明健康调查问卷SF-12对入选223例COPD患者行问卷调查,计算不同COPD分级的躯体成分(PCS)评分和精神成分(MCS)评分。根据支气管舒张试验将COPD患者223例分为支气管舒张试验阳性和阴性两组,观察患者肺功能与生活质量的关系。结果COPD患者PCS及MCS评分与COPD分级呈负相关(rPCS=-0.282,P<0.05;rMCS=-0.172,P<0.05)。223例患者支气管舒张试验阳性77例,阴性146例。支气管舒张试验阳性者PCS评分高于阴性者(t=3.331,P<0.01)。结论COPD患者肺功能与生活质量密切相关,肺功能联合生活质量评价能更全面地反映患者病情的严重程度。更多还原

【Abstract】 Objective To observe the correlation between quality of life and lung function in patients with chronic obstructive pulmonary disease(COPD)in stable phase.Methods The quality of life in 223 patients with COPD in stable phase were asked by concise health survey questionnaire(SF-12)developed by Boston Institute of Health.Physical component summary(PCS)scores and mental component summary(MCS)scores were counted in different classification of COPD.The 223 patients were divided into positive group and negative group according to the results of bronchial dilation test,and the relationship between lung function test and the quality of life were observed.Results PCS scores and MCS scores were negatively associated with grade of COPD disease(rPCS=-0.296,P<0.05,rMCS =-0.146,P<0.05).In the bronchodilation tests,77 patients were positive,146 patients were negative.PCS scores of the positive patients were higher than that of the negative ones(t=3.331,P<0.01).Conclusions The lung function of COPD patients is closely related to the quality of life.Lung function test combined with quality of life in COPD patients could more roundly reflect the severity of disease.更多还原