【摘要】 目的探讨氨磺必利治疗精神分裂症患者的临床疗效。方法选择符合条件的精神分裂症患者40例,阳性亚型组以≥400mg/d为起始剂量,阴性亚型组以100～300mg/d为起始剂量的氨磺必利治疗10周,疗效评定采用阳性与阴性量表(PANSS)。结果治疗结束时,痊愈5.1%,显效69.2%,有效25.6%,PANSS量表总分及分量表分与治疗前比较均有显著性差异。结论氨磺必利对精神分裂症的阳性及阴性症状均有疗效,且以较低剂量即能明显改善阴性症状为突出特点。更多还原

【Abstract】 Objective To study the clinical effect of amisulpride in theatment patients with schizophrenia. Methods Forty schizophrenic patients were treated with amisulpride for 10 weeks,with the beginning dosage of 400mg/d for amisulpride in positive group and 100~300mg/d for amisulpride in negative group.The efficacy was assessed with PANSS.Results The total score and factor scores of PANSS significantly decreased after treatment. The recovery rate was 5.1%,the excellent effective rate was 69.2%,and the effective rate was 25.6%.Conclusion Amisulpride is effective on both positive and negative symptoms in schizophrenia,especially on negative sympotoms in lower dosage.更多还原