【摘要】 目的评估颅内埋置电极脑电图(iEEG)监测定位致痫灶的意义和安全性。方法头皮脑电图(sEEG)监测致痫灶定位困难的顽固性癫痫患者27倒。采用颅内硬膜下和/或脑内电极长程视频脑电监测,根据术中癫痫放电的表现,术后病理结果,疗效和脑电图复查结果分析颅内电极脑电监测定位致痫灶的准确性。结果18例埋置硬膜下电极,7例联合应用硬膜下电极和深度电极,2例埋置深部电极,颅内电极埋置1～6d,平均3.1d,脑电监测24～140h,平均70h。根据癫痫发作初始期iEEG23例患者准确定位了致痫灶。无颅内出血和感染等严重并发症。结论对于那些无创检查不能明确致痫灶的患者iEEG是一种安全可靠的定位方法。更多还原

【Abstract】 Obejctive To investigate the role and the safety of chronic instracranial EEG recording in patients with instractable epilepsy for localizing epileptogenic zone.Methods The subdural and/or depth electordes were implanted in 27 patients.Epileptogenic zones were determined according to the performances of long-term video iEEG.The accuracy for localization of epileptogenic zones were accurate based on the data of iEEG minitoring,pathological examination,postoperative EEG recording and clinical follow-up.Results Subdural electordes were used in 2 patients,depth electordes in 18 patients,both subdural and depth electordes in 7 patients.The electordes were implanted for 1～6 days (means 3.1 days),and the iEEG minitoring lasted from 24 to 140 hours( mean 70 hours). 23 patients with instractable epilepsy for localizing epileptogenic zone relied on the iEEG of the beginning of epilepsy. No significant complications were observed. Conclusion The implantation of subdural and depth electordes to localize epileptogenic zone in selected patients is a safe and effective method.更多还原