【摘要】 目的观察地塞米松预防剖宫产患者自控镇痛致恶心、呕吐、瘙痒等不良反应疗效。方法选择同期妇产科硬膜外麻醉手术患者。Ⅰ组(实验组):剖宫产手术50例,Ⅱ组(对照组):妇科手术50例。两组于手术结束时施行患者自控硬膜外镇痛,同时Ⅰ组静脉注射地塞米松10 mg;Ⅱ组静脉注射格拉司琼4mg。观察记录患者镇痛效果(视觉模拟评分法)及恶心、呕吐、胃肠恢复、瘙痒等不良反应的发生率。结果镇痛效果确切,两组比较差异无统计学意义(P>0.05),不良反应:恶心、呕吐发生率两组差异无统计学意义(P>0.05),皮肤瘙痒发生率及胃肠恢复延长Ⅰ组低于Ⅱ组(P<0.05)。结论地塞米松能有效预防剖宫产患者自控镇痛所致恶心、呕吐、皮肤瘙痒等不良反应。更多还原

【Abstract】 Objective To investigate the effect of dexamethasone in the the prevention of untoward responses such as vomit,nausea and itch,caused by using patient-self controlled epidural analgesia after cesarean section.Methods Post-operative gynecological patients and cesarean women operated under epidural block were selected.The first group(experiment group) cesarean section 50 cases.The second group(contrast) gynecological operation 50 cases.P.C.E.A.(patient self-controlled epidural analgfesia) was carried out in both groups.The first group was treated with dexamethasone 10 mg I.V.The second group was treated with granisetron 4mg I.V.the analgesic effect,nausea,vomit,skin-itch and the time for recovery of digestive function were closely observed and recorded.Results The analgesic effect is excellent,there is no significant difference between,these two groups(P>0.05).Of untoward responses such as nausea,voimit,no obvious difference is observed between these two groups(P<0.05).The skin-itching rate is lower in group Ⅰand the time for digestive function recovery is shorter in group Ⅰ too.Conclusion Desamethasone can be effectively used to prevent these untoward responses such as nausea,vomit and skin-itching from using patient self-controlled epidural analgesia by women after cesarean section.更多还原