【摘要】 目的观察马来酸曲美布汀联合双歧杆菌对功能性肠胀气的疗效。方法将功能性肠胀气患者随机分为A、B两组,每组30例。A组服用马来酸曲美布汀联合双歧杆菌,B组仅服用双歧杆菌,疗程2周。结果治疗1周,A组症状积分明显下降(P<0.01),B组无明显变化(P>0.05)。治疗2周,A组症状积分下降更为明显(P<0.01),B组较治疗前明显下降(P<0.05),但高于A组(P<0.05)。A组总有效率明显高于B组(1周有效率:腹胀:53.3%VS 17.9%,伴随症状:58.3%VS 28.6%;2周有效率:腹胀:76.7%VS 42.9%,伴随症状:79.2%VS 45.5%)。结论马来酸曲美布汀联合双歧杆菌对功能性肠胀气有较好疗效。更多还原

【Abstract】 Objecctive To evaluate the efficacy of trimebutine mateate combined with bifidobacterium in treatment of overful gas in intestinal tract of patients with alimentray dyskinesia.Methods By using a randomized and controlled clinical trial,the patients were divided into trimebutine maleate combined with bifidobacterium group(A group,n=30)and bifidobacterium group(B group.n=30).The treatment duration was 2 weeks.Results The symptom scores in A group decreased significantly(P<0.01)after l week treatment and more remarkably(P<0.01)after 2 weeks treatment.In B group,the symptom scores decreased significantly(P<0.05)only after 2 weeks treatment,and higher than A group(P<0.05).Total efficacy rate of A group were higher than B group(1st week efficacy rate:abdominal distension:53.3%VS l7.9%.other symptoms:58.3%VS 28.6%.2nd week efficacy rate:abdomihal distension:76.7%VS 42.9%,other symptoms:79.2%VS 45.5%).Conclusion Trimebutine maleate combined with bifidobacterium is effective in treatment of patients with overful gas in intestinal tract.更多还原