【摘要】 目的探讨焦虑障碍听觉认知性电位P300的特点。方法对32例焦虑障碍患者(AN组)和30名健康成年人(NC组),应用美国脑诱发电位仪进行P300检测。结果与NC组相比,AN组Oz点P3潜伏期后移[NC组(328±16)ms,AN组(340±18)ms,t=2.801,P<0.01],P3波幅降低[NC组(6.1±2.0)μV,AN组(4.6±2.2)μV,t=2.84,P<0.05],非靶P2波幅降低[NC组(3.1±0.8)μV,AN组(1.9±0.9)μV,t=5.61,P<0.01]。结论焦虑障碍认知性电位P300变化诸特点值得进一步随访。更多还原

【Abstract】 Objective To study characteristic of event-related potentials P300 (P300) in patients with anxiety disorder.Methods With American Nicolet Bravo Instrument,P300 test was carried out in 32 patients with anxiety disorder and 30 healthy adult controls.Results Patients with anxiety disorder had significant delayed P3 latency [NC(328±16)ms,AN(340±18)ms,t=2.801,P<0.01],decreased P3 [NC(6.1±2.0)μV,AN(4.6±2.2)μV,t=2.84,P<0.05] and P2 [NC(3.1±0.8)μV,AN(1.9±0.9)μV,t=5.61,P<0.01] amplitude of P300 than those of the controls.Conclusion The characteristics of P300 of anxiety disorder patients deserve further following up.更多还原