【摘要】 目的探讨慢性疲劳综合征患者在睡眠状态下脑电生理活动的变化。方法应用日本Nihon Kohden公司的Neurofax-1518K多导睡眠生理仪,采用眼电图和下颌肌电图及脑电图技术,对25例慢性疲劳综合征患者和33名正常对照者进行多导睡眠图(PSG)整夜监测。结果与正常对照组比较,慢性疲劳综合征组总记录时间延长[(488.7±21.7)分对(515.9±31.7)分,P<0.05],睡眠潜伏期延长[(19.9±9.8)分对(40.1±11.7)分,P<0.01],第1阶段睡眠增加[(9.1±1.9)%对(14.9±7.9)%,P<0.01],第2阶段睡眠减少[(56.2±4.7)%对(48.8±18.7)%,P<0.05],以及与神经症相似的REM结果(REM潜伏期前移,REM活动量、强度和密度)均增加。结论慢性疲劳综合征组的睡眠结构紊乱类似于神经症。更多还原

【Abstract】 Objective To assess the changes of the whole night polysomnography (PSG) in patients with chronic fatigue syndrome(CFS). Methods The changes of the whole night PSG were recorded and compared between 25 patients with CFS and 33 normal subjects,by using Neurofax-1518K (Nihon Kohden) sleep instrument. ResultsCompared with normal subjects,CFS patients showed significantly reduced total sleep duration \[(488.7±21.7)min vs (515.9±31.7)min,P<0.05\],prolonged sleep latency \[(19.9±9.8)min vs (40.1±11.7)min,P<0.01\],increased stage 1 sleep \[(9.1±1.9)% vs (14.9±7.9)%,P<0.01\],decreased stage 2 sleep\[(56.2±4.7)% vs (48.8±18.7)%,P<0.05\],as well as the REM changes similar to that showed in patierots with neurosis (shortened REM latency,REM activity,density). Conclusion Patients with CFS exhibit abnormality in sleep frame similar to that in neurosis.更多还原