Objective To explore the relationship between carotid intima-media thickness(IMT) and metabolic indices in newly diagnosed type-2 diabetic patients,and the risk factors of atherosclerosis(AS).Methods 44 normal control subjects(NC),42 obese subjects with normal glucose tolerance(Ob) and 60 newly diagnosed type-2 diabetes mellitus subjects(T2DM) were recruited.Body mass index(BMI),waist-to-hip ratio(WHR),systolic blood pressure(SBP),diastolic blood pressure(DBP),triglycerides(TG),cholesterol(TC),low-density l...
【基金】
广东省肇庆市科技创新计划立项(No.2006E114)
【更新日期】
2009-07-10
【分类号】
R587.1
【正文快照】
动脉粥样硬化(AS)性血管疾病是糖尿病的严重并发症,AS的发生与血糖升高、高血压、胰岛素抵抗(IR)、中心性肥胖及血脂异常为特征的代谢综合征密切相关[1]。国内已有文献报道糖耐量受损(IGT)是早期AS的独立危险因素[2]。那么随着IGT向T2DM的进展,众多代谢异常因表1一般Tab.1The c