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酸枣仁茶改善小鼠睡眠作用的研究
Effect of Semen Ciziphi Spinosae tea on sleeping quality of mice
【摘要】 目的研究酸枣仁茶改善小鼠睡眠作用的影响。方法分别以334、667、1 334mg/kg BW剂量的酸枣仁茶给小鼠连续灌胃30d后,通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、巴比妥钠阈下剂量催眠实验和巴比妥钠睡眠潜伏期实验,观察不同剂量酸枣仁茶对小鼠睡眠的影响。结果酸枣仁茶能显著延长戊巴比妥钠睡眠时间(P<0.01)、且睡眠发生率明显增加(P<0.05)、缩短巴比妥钠睡眠潜伏期(P<0.01),且无直接催眠作用,对小鼠的体重无明显影响。结论该酸枣仁茶具有改善小鼠睡眠的作用。
【Abstract】 Objective To investigate the effect of Semen Ziziphi Spinosae Tea on the sleep of mice.Methods Semen Ziziphi Spinosae Tea was consecutively orally given to mice with the doses of 334,667,1334 mg/ kg of body weight for 30 days.The effects of sleep improvement of the three dosages of Semen Ziziphi Spinosae Tea were observed.Results The sleep time of mice was prolonged obviously(P<0.01),the sleeping rate of mice was increased obviously(P<0.05),the sleep incubation period was decreased significantly(P <0.01),and there no indirect sleep-inducing effect was observed.Conclusion Semen Ziziphi Spinosae Tea can improve the sleeping quality of the mice.
- 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2009年09期
- 【分类号】R285.5
- 【被引频次】5
- 【下载频次】466