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老年肺心病患者肺部非发酵菌感染与耐药性分析
Drug resistance and pulmonary non-fermentive bacterium infection in senile pulmonary heart disease patients
【摘要】 目的探讨老年慢性肺源性心脏病(肺心病)患者肺部非发酵菌感染和耐药情况。方法对老年肺心病患者的痰培养分离出的非发酵菌种类及药敏情况进行分析。结果126例老年肺心病患者痰标本共分离出非发酵菌107株,其中铜绿假单胞菌55株,鲍曼/溶血不动杆菌28株,嗜麦芽窄食单胞菌15株。药敏结果显示,非发酵菌对第三代头孢菌素的耐药已十分显著,平均耐药率达50%~100%;含酶抑制剂复方型抗菌药物特美汀、舒普深、亚胺培南及左氧氟沙星耐药率低(3.6%~35.7%),与三代头胞及其他抗菌药物相比差异有显著性(P<0.05)。结论老年肺心病患者肺部非发酵菌感染耐药率高,宜选用复合抗菌药物对非发酵菌感染者进行的治疗。
【Abstract】 Objective To analyze the status of Nonfermenters infection in chronic pulmonary heart disease in senile patients and its drug resistance. Methods Pulmonary heart disease in senile patients with isolated sputum culture of nonfermentative bacteria type and drug sensitivity were analyzed retrospectively. Results There 107 nonfermenter strains were isolate4d from 126 senile pulmonary heart disease patients,inclduing 83 Pseudomonas aeruginosa strains,28 Baumanii / haemolytius Acinetobacter strains,15 Mal-tophilia strains. The average resistance of nonfermenters to the third-generation of cephalosporin were 50% ~100% ; inclduing augmentin,sulperazon,imipenem and levofloxacin. Conclusion The resistance of nonfermenters in senile pulmonary heart disease patients to antibiotics is high and appropriate drug be selected for treatmetn nonfermenters infection.
【Key words】 Pulmonary heart disease; Nonfermenters; Pseudomonas; Acinetobacter; Drug resistance;
- 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2009年08期
- 【分类号】R446.5;R541.5
- 【被引频次】1
- 【下载频次】48