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妊娠合并甲状腺功能减退症临床分析

Clinical analysis of pregnant patients complicated with hypothyroidism

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【作者】 刘小玲叶振海吴超平林卡妮

【Author】 LIU Xiao-ling,YE Zhen-hai,WU Chao ping,et al.(Wuchuan Municipal Maternal Hospital,Wuchuan 524500,Guangdong,P.R.China)

【机构】 吴川市妇幼保健院妇产科

【摘要】 目的探讨妊娠合并甲状腺功能减退症的临床特点、病因、危害和治疗。方法回顾性对比分析2007年1月~12月吴川市妇幼保健院住院的2200例妊娠病例资料分析,比较和总结其中56例妊娠合并甲状腺功能减退的临床特点、病因、危害和治疗。结果本组2200例妊娠病例中,56例妊娠合并甲状腺功能减退症,发生率为2.55%。亚临床甲减50例,发生率为2.27%,临床甲减6例,发生率0.27%。妊娠合并桥本氏甲状腺炎18例其中3例甲减,发生率0.135%。结论孕妇中甲减的发生率尤其是亚临床甲减的发生率并不低,妊娠期甲减的病因主要是桥本氏甲状腺炎,妊娠期高血压疾病和胎儿宫内窘迫是妊娠期甲减的主要并发症。妊娠期甲减的治疗首选左旋甲状腺素(L-T4)替代治疗。

【Abstract】 Objective To discuss the clincal feaures,causes,lesions and treatment of pregnant women complicated with hypothyroidism.Methods There 2 200 pregnant women complicated with hypothyroidism admitted in Huizhou Municipal Maternal Hospital from January to December 2007 were retrospectively analyzed.Results There 56 pregnant complicated with hypothyroidism(2.55%),50 with subclinical hypothyroidism(2.27%),9 with clinical hypothyroidism cases(0.27%) and 18 with Hashimoto thyroiditis(including 3 hypothyroidism cases).Conclusion Hashimoto thyroiditisis is the main cause for pregnant women complicated with hypothyroidism.Pregnancy-induced hypertantion and fetal distresws are the main complications during pregnancy,and levothyroxine is the drug of choice for treatment of the disease.

【关键词】 妊娠甲状腺功能减退症替代治疗
【Key words】 PregnancyHyperthyroidismTreatment
  • 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2009年07期
  • 【分类号】R581.2;R714.2
  • 【被引频次】5
  • 【下载频次】343
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