【摘要】 目的了解湖北省1951~2006年流行性乙型脑炎(乙脑)流行特征,分析乙脑监测结果,为防制提供科学依据。方法对湖北省疫情信息管理系统的疫情资料及2005~2006年全国乙型监测点资料进行分析。结果累计报告乙脑病例130 304例、累计死亡数为16 227例;年发病率波动在0.14/10万~33.69/10万之间。90年代后期以后以鄂西地区发病率较高。高发季节在5~10月,10岁以下儿童占90.74%,男女发病比例为1.77:1,病例以散居儿童为主(59.49%),其次为学生(34.24%)。媒介蚊密度从6月份开始增加,9月上旬达最高。猪血清乙脑IgG抗体总阳性率72.19%。正常人群血清IgG抗体总阳性率约35%。临床病例实验室确诊率50%。结论流行趋势和流行地区的改变与乙脑疫苗的使用密切相关,要加强乙脑监测及预测预警,采取加强10岁以下儿童乙脑疫苗接种和防蚊灭蚊为主的防控措施。更多还原

【Abstract】 Objective To understand the epidemic situation of Japanese B encephalitis(JE) in Hubei and provide scientific basis for controlling JE in the future.Methods The data of JE from NNDRS and surveillance spots in Hubei was analyzed by Excel 2003.Results The accumulative total JE cases was 130 304 and 16 227 deaths.The annual average incidence flunctuated from 0.14/100 000 to 33.69/100 000 and it was higher in the west mountainous areas in this province..High peak period was from July to August.The retios of male to female was 1.77 : 1.Scattered living children was accounted for 59.49% and students 34.24%.Mosquito density increased since June and the peak was in September.The average positive rate of serum antibody IgG in pigs was 72.19%,and that in health population was 35%.The rate of clinical laboratory diagnosis was of JE cases was 50%.Conclusion The change of epidemic trend and areas was associated with JE vaccine immunization.The work of surveillance and forecast should be strengthened and vaccination of the children under 10 years old and control of mosuitoes are the main preventive strategy.更多还原