【摘要】 目的:总结141例甲状腺微小癌(thyroid microcarcinoma,TMC)的诊治经验。方法:回顾性分析1985-06-2006-09我们收治的141例TMC患者的临床病理资料。结果:其临床表现大多为症状不典型、病灶小和隐匿。141例TMC均经手术治疗,其中患侧腺叶近全切除术26例(18.4%),患侧腺叶全部加对侧次全切除术81例(57.4%),全甲状腺切除术34例(24.1%),其中加颈部区域性淋巴结清除14例(10.0%)及加功能性淋巴结清除6例(4.3%)。手术切除率100%,无手术死亡。71例(50.4%)术后随访1～13年,1例局部复发,1例术后12年因肺脏转移死亡。12例行免疫组化检查,11例(91.7%)细胞角蛋白19(CK19)阳性。结论:手术是治疗TMC的唯一有效方法,配合CK19等免疫标志检查可提高TMC的病理诊断正确率。更多还原

【Abstract】 OBJECTIVE:To summarize the diagnosis and surgical treatment of thyroid microcarcinoma.METHODS:The clinical data of thyroid microcarcinoma of 141 cases were retrospectively analysed from Jun.1985 to Sep.2006.RESULTS:The clinical manifestations were not differential and the symptoms were atypical.All the patients were cured with operation and without mortality.The 141 cases of thyroid microcarcinoma underwent one lobectomy(26 cases,18.4%),near total thyroidectomy(81 cases,57.5%),total thyroidectomy(34 cases,24.1%),total thyroidectomy with local neck dissectionand(14 cases,10.0%),and that with functional neck dissection(6 cases,4.3%).Resection rate was 100%.The follow-up rate was 50.4%(71 cases) with time ranging from 1 year to 13 years.The Immunohistochemical results in 12 cases showed positive cytokeratin 19(CK19) in 11 cases(91.7%).CONCLUSIONS:Surgery is the main method of final diagnosis and treatment.The application of immunohistochemical marker such as CK19,etc is supplementary to pathological dignosis.更多还原