【摘要】 目的:探讨Tis-1N0M0期低位直肠癌经肛门局部切除的合理性。方法:回顾性分析1996-01-01-2002-12-30经肛门局部切除治疗的53例Tis-1N0M0期直肠癌患者的资料。其中TisN0M018例,T1N0M035例。6例T1患者接受了术后放疗。结果:所有患者术后恢复良好,住院时间7d(5～8d)。无吻合口漏、直肠狭窄、肛瘘及其他手术并发症。术后肛门括约肌功能良好。总5年生存率为98.11%(52/53),Tis、T1期5年生存率分别为100%(18/18)和97.14%(34/35)。总5年复发率为3.78%(2/53),Tis、T1期5年复发率分别为0(0/18)、5.71%(2/35)。结论:对Tis-1N0M0期低风险低位直肠癌患者,经肛门局部切除术既保证了生存率,又兼顾了患者的生存质量,是一种较为理想的术式选择。更多还原

【Abstract】 OBJECTIVE:To assess the validity of transanal excision for Tis-1N0M0 rectal cancer as an effective treatment.METHODS:Fifty three patients with stage Tis-1N0M0 rectal cancers underwent transanal local excision(Tis:18,T1:35),and 6 T1 patients also received post-operative radiation therapy.The clinical data were analysed.RESULTS:There was no perioperative death.Fecal continence was postoperatively good.The overall 5-year survival rate was 98.11%(52/53),and the 5-year survival rate was 100%(18/18)for Tis and 97.14%(34/35)for T1.The overall 5-year tumor recurrence rate was 3.78%(2/53),the local tumor recurrence rate was 0(0/18)for Tis,and 5.71%(2/35)for T1.CONCLUSION:The transanal local excision for Tis-1N0M0 low rectal cancer results in a low complication rate and good sphincter function,and provides a satisfactory local control and 5-year survival rate.更多还原