【摘要】 目的探讨肾上腺外嗜铬细胞瘤的诊治方法。方法对37例肾上腺外嗜铬细胞瘤的临床资料进行回顾性分析。结果86.5%的患者有高血压,24h尿儿茶酚胺和香草基扁桃酸增高者分别为86.7%及80.0%,血肾上腺素和去甲肾上腺素检查增高者分别为6/7及5/7。经腹部B超、CT、MRI等检查进行定位诊断。肾上腺外嗜铬细胞瘤占同期治疗的嗜铬细胞瘤患者的14.0%。成功行肿瘤切除术者占89.2%,恶性者占16.2%。结论尿儿茶酚胺和香草基扁桃酸以及血肾上腺素和去甲肾上腺素对于肾上腺外嗜铬细胞瘤的诊断具有重要意义,增强三维CT应作为首选的定位方法。肾上腺外嗜铬细胞瘤容易复发,对于复发病例应争取手术治疗。更多还原

【Abstract】 Objective To study the diagnosis and treatment of extra-adrenal pheochromocytoma.Methods The clinical data of 37 patients of extra-adrenal pheochromocytoma were retrospectively analyzed.Results There were 86% of the patients who had hypertension,86.7% whose 24 h urine catecholamine increased and 80% whose vanillylmandelic acid increased,88.9% whose plasma epinephrine increased and 71.4% whose norepinephrine increased.The foci were localized mainly by abdominal ultrasonography,CT and MRI.The patients with extra-adrenal pheochromocytoma accounted for 14.0% of all the concurrent patients with pheochromocytoma.Tumor resection was successfully performed in 89.2% patients,and 16.2% of the foci were malignant.Conclusion Urine catecholamine and vanillylmandelic acid,plasma epinephrine and norepinephrine are of important significance for the diagnosis of extra-adrenal pheochromocytoma.Three dimensional enhanced CT scanning can be the first choice of localization.Relapse is rather common in this disease;the recurrent case should be managed with surgical operation.更多还原