【摘要】 目的:探讨肾上腺素在经导管肝动脉化疗栓塞术(transcatheter hepatic arterial chemoembolization,TACE)治疗中晚期肝癌中的应用价值。方法:144例中晚期肝癌患者随机分成2组,治疗组72例,在灌注化疗药物及碘油乳剂前推注小剂量肾上腺素;对照组72例,常规行经导管肝动脉化疗栓塞术,2组所用化疗药物及超液态碘油基本相同。结果:治疗组有效率为61.11%,对照组为36.11%,治疗前后肝肿瘤的变化、术后肝功能变化及对生活质量的影响2组差异有统计学意义(P<0.05)。结论:小剂量肾上腺素经导管灌注可显著减少TACE术后肝功能损害。更多还原

【Abstract】 Objective:To investigate the application value of adnephrin in TACE on the apud -advanced liver cancer. Methods:144 patients with apud -advanced liver cancer were randomly divided into two groups,In treatment group of 72 cases,patients were injected small dose of epinephrine prior to the chemotherapy drugs and lipiodol emulsion ; In control group of 72 cases,patients were treated with conventional chemotherapy and embolism,which the chemotherapy drugs and lipiodol ultra liquid were the same basically. Results:The efficiency of the treatment group was 61.1%,36.1% for the control group.The changes of intrahepatic tumor、postoperative liver function and the quality of life had a significant deviation in two groups between pretherapy and post-treatment (P<0.05). Conclusion:The small dose epinephrine infusion transcatheter can significantly reduce damage to liver function after TACE.更多还原