【摘要】 目的探讨糖基化终末产物与冠心病、糖尿病的相关性。方法分别检测正常对照组、冠心病组、糖尿病组及糖尿病并发冠心病组的血清糖基化终末产物、糖化血红蛋白,并进行相关分析。结果各观察组血清糖基化终末产物均较正常对照组升高,且各组间的差异有统计学意义(P<0.05),糖基化终末产物与糖化血红蛋白呈正相关(r=0.738,P=0.000)。结论血清糖基化终末产物与冠心病具有相关性,并且是糖尿病心血管合并症的相关危险因素。更多还原

【Abstract】 Objective To explore the relationship between advanced glycation end products(AGE),coronary heart disease(CHD)and diabetes.Methods AGE and HbA1c were tested in each group,including control,CHD,TypeⅡdiabetes mellitus(DM),both CHD and DM group.Correlative analysis was carried out.Results AGE were significantly higher in each observational group compared to that in control group(P<0.05).AGE was significantly positively correlated with HbA1c(r=0.738,P=0.000).Conclusions AGE is correlated with CHD,it’s a risk factor relate to diabetic cardiovascular disease.更多还原