【摘要】 目的了解和分析上海农村社区≥50岁人群卒中危险因素暴露状况及卒中风险水平。方法采取整群抽样的方法,于2008年对上海奉贤区某农村社区50~74岁人群进行卒中危险因素现况调查和脑血流动力学指标(CVHI)检测,分析人群危险因素暴露水平,并以CVHI积分值作为评价卒中风险的指标。选择经济条件、生活环境和医疗卫生水平基本一致,年龄、性别相匹配的相邻社区2003年的资料,对比危险因素暴露水平。结果纳入调查且资料完整的调查对象8350人(男3585人,女4765人)。①危险因素的暴露率分别为:高血压50.1%、心脏病7.3%、糖尿病4.5%、血脂异常4.4%、肥胖10.0%、卒中家族史7.3%;男女性别间差异有统计学意义的危险因素分别为高血压(男性为53.5%,女性为47.5%)和血脂异常(男性为5.4%,女性为3.7%),均P<0.01。②CVHI积分值随年龄增长而下降,女性CVHI积分值低于男性,P<0.01。该人群中23.9%(1993/8350)存在脑血流动力学(CVHI积分值<75分)异常;男性为21.1%(758/3585),女性为25.9%(1235/4765);8350人中,脑血流动力学重度异常者(CVHI积分值<25分)占4.8%(404/8350)。男性发生率为4.4%(156/3585),女性为5.2%(248/4765)。③与2003年相邻社区的调查结果相比,除心脏病外,其他危险因素暴露水平均明显升高(P<0.05)。结论上海农村社区≥50岁人群卒中危险因素高血压居首位;近1/4人群有脑血管血流动力学异常,为卒中高危人群。更多还原

【Abstract】 Objective To investigate and analyze the exposure of stroke risk factors and the risk of stroke in a population aged ≥50 years of age in Shanghai rural community.Methods A cluster sampling method was used to perform a cross profile study on the risk factors of stroke and cerebrovascular hemodynamic indexes(CVHI) detection in a population aged 50-74 years in a rural community of Shanghai in 2008.The exposure degree of risk factors in the population was analyzed,and the CVHI integral value was used as an indicator for the evaluation the risk of stroke.The economic condition,living environment,and medical service of the patients were basically the same.The age and sex matched data in a neighboring community in 2003 were used to compare the levels of risk factor exposure.Results A total of 8350 subjects with complete data were included in the survey(male 3585,female 4765).①The exposure rates of hypertension,heart disease,diabetes,lipid abnormality,obesity,and family history of stroke were 50.1%,7.3%,4.5%,4.4%,10.0%,and 7.3%,respectively;The significant sexual difference risk factors were hypertension(men 53.5%,women 47.5%) and lipid abnormality(men 5.4%,women 3.7%).②The integral value of CVHI decreased with age,and lower in women(P<0.01).In this population,23.9% of subjects existed hemodynamic abnormalities(CVHI integral value <75) in the cerebral blood vessels;in men were 21.1%,and in women were 25.9%;Among the 8350 subjects,severe hemodynamic abnormalities(CVHI integral value <25) in blood vessels of brain accounted for 4.8%,in men were 4.4%,and in women were 5.2%.③In addition to heart disease,the exposure rate of other risk factors were increased significantly as compared to the findings in the neighboring community in 2003(P<0.05).Conclusion Of the risk factors of stroke in the population aged ≥50 years in Shanghai rural community,hypertension ranked the first.About one quarter of the population had hemodynamic abnormalities,and they were the high-risk population susceptible to stroke.更多还原