【摘要】 为了减少频域光学层析成像(spectral domain optical coherence tomography,SDOCT)中的噪声干扰,应用相位偏移干涉技术消除SDOCT系统中的自相关噪声与虚像.分析了主要影响因素位移标定误差对噪声消除的影响.通过载玻片实验指出五相位偏移法对压电陶瓷晶体(PZT)相位偏移位移标定误差最不敏感.在10%的移相误差下,五相位偏移法使载玻片成像图中自相关项的强度仍然接近于0并使虚像信号的强度在0.25以内.离体兔眼角膜实验结果验证了三相位以上(含三相位)的相位偏移方法能够同时消除虚像及自相关噪声,且在实验过程中避免了实虚像重叠及等光程点的设置.更多还原

【Abstract】 To decrease the noise in spectral domain optical coherence tomography (SDOCT), phase shifting interferome-try was applied to eliminating the autocorrelation noise and virtual image in SDOCT. And the main factor affecting the quality of noise elimination is miscalibration error. Results of the slide imaging experiment show that five-phase shifting method is the most insensitive to PZT phase-shifting miscalibration error; it controls the autocorrelation term near zero and virtual image under 0.25 in intensity, with 10% miscalibration error. Moreover, in the experiment of in vivo rabbit cornea imaging, over three-phase (including three-phase) shifting methods can eliminate the virtual image and autocorrelation noise, simultaneously avoiding the overlapping between the real and virtual images, and the setting of optical path length (OPL) matching point in experimental process.更多还原