【摘要】 目的:探讨感染中毒症患者血清神经元特异性烯醇化酶(NSE)的变化及意义。方法:用双抗体夹心法测定52例感染中毒症患者血清NSE浓度。结果:感染中毒症组血清NSE浓度显著高于对照组(P<0.05);严重感染中毒症和感染中毒症休克组血清NSE浓度显著高于普通感染中毒症组(P<0.01),普通感染中毒症组血清NSE浓度与对照组相比差异无统计学意义(P=0.055)。结论:血清NSE浓度升高可作为提示感染中毒症患者神经元细胞受损的辅助性指标,也是判断病情预后的指标之一。更多还原

【Abstract】 Objective:To explore the changes of neuron-specific enolase(NSE) in patients with sepsis and its significance.Methods:Levels of NSE in 52 patients with sepsis were detected by the method of double antibody sandwich.Results:Levels of NSE was significantly higher in sepsis group than those of the control group(P<0.05).Levels of NSE were significantly higher in severe sepsis and septic shock group than those of the ordinary sepsis group(P<0.01).There was no significant difference in level of NSE between the ordinary sepsis group and the control group(P=0.055).Conclusions:NSE can be used to detect damage of nerve cell in patients with sepsis and may be regarded as one of the indicators in predicting the prognosis.更多还原