【摘要】 从变绿红菇子实体中提取出4种多糖,检测了它们的化学组成和分子量,并通过体内和体外实验,检测其抗肿瘤活性。结果表明,变绿红菇子实体的4种多糖为杂多塘,含有的单糖组分分别为木糖、葡萄糖、半乳糖、甘露糖以及果糖,其中葡萄糖为主要单糖组分。这4种多糖的重均分子量分别为3.1×107,6.5×105,5.1×105,8.0×105Da;多糖RVP2有较好的抗肿瘤活性,此发现为变绿红菇的深入开发利用提供了有价值的依据。更多还原

【Abstract】 Four water-soluble polysaccharides were sequentially extracted from the fresh fruiting bodies of Russula virescens,and their chemical and physical characteristics were determined. The antitumor activities against Sarcoma 180 tumor cell (S-180) were then tested both in vitro and in vivo. The heteropolysaccharides consisted of xylose,mannose,glucose,galactose,and fructose. The weight average molecular weights (MWs) of polysaccharides RVP1,RVP2,RVP3,and RVP4 were determined to be 3.1×107,6.5×105,5.1×105,and 8.0×105 Da,respectively. Except for RVP2,the other three polysaccharides were ineffective in suppressing S-180 growth. This find can the utilization of Russula virescens.更多还原