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自体角膜缘干细胞移植联合丝裂霉C、逆行性翼状胬肉切除术的疗效观察

Effects of auto-corneal limbus stem cell transplantation combined with mitomycin ctreatment in the improved pterygium surgery

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【作者】 邵杰刁路明

【Author】 SHAO Jie1,2,DIAO LuMing1.1 Pathology Teaching Room,Preclinical Medical College of Wuhan University,Wuhan,430072,China.2 Department of Ophthalmology,People’s Hospital of Yunyang medical college of Shiyan,Shiyan,442000,China.

【机构】 湖北省武汉大学基础医学院郧阳医学院附属十堰市人民医院眼科

【摘要】 目的探讨逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉的临床效果和安全性。方法选取69例(76眼)翼状胬肉患者,采用逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C进行治疗然后进行随访观察。结果所有患者均接受了10~13.5月(平均12月)以上的随访,有3例患者复发,没有发现任何并发症。结论逆行性翼状胬肉切除、自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉是一种简便、安全有效的治疗方法。

【Abstract】 Objective To explore the clinical effect and safety of auto-corneal limbus stem cell transplantation combined with MMC in the treatment of improved pteryglum surgery.Methods 46 patients(50 eyes)with pterygium received improved pterygium excision operation.During the surgery,the entire pterygium was striped with comeal epithelium,bare sclera was exposed to 0.2g /L MMC for 2~3min,the eyes were given auto-corneal limbus stem cell transplantation.Results All the cases were followed up for average 12 mo.the pterygium recurrence appeared in two eyes and no serious complication were observed.Conclusion These findings suggest that in the pterygium improved surgey auto-corneal limbus stem cell transplantation combined with topical MMC can significantly decrease the recurrence rate of pterygium,and it is a convenient,safe and effecfive method.

  • 【文献出处】 中国老年保健医学 ,Chinese Journal of Geriatric Care , 编辑部邮箱 ,2009年01期
  • 【分类号】R779.6
  • 【下载频次】18
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