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血脂异常与2型糖尿病和性别的相关研究 社区人群心脑血管事件前瞻性研究系列之六
The relationship of blood-lipid disorder with the prevalence of type 2 diabetes mellitus and sex in the people of Nanning city,Guangxi province
【摘要】 目的研究血脂异常与2型糖尿病和性别的关系。方法将广西南宁市年龄36~78岁,平均年龄(54.23±9.87)岁的1072人分为2型糖尿病组与正常组,测定甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)及腰围(Waist)、体重指数(BMI)等相关指标,探索血脂异常与2型糖尿病和性别关系。结果①与正常组相比,2型糖尿病组总胆固醇(TC),甘油三酯(TG),高密度脂蛋白(HDL)含量有显著性差异(P分别为0.0081、0.0015、<0.0001)。②甘油三酯和胆固醇异常为糖尿病的风险因素,男性高胆固醇(TC)与糖尿病的关联比女性大(OR1.93:1.49),女性高甘油三酯(TG)与糖尿病的关联比男性大(OR2.49:1.46)。结论2型糖尿病患者血脂比健康人群高,应预防高血脂,降低疾病风险。血脂含量异常与糖尿病、性别具有相关关系。
【Abstract】 Objective To investigate the relationship of blood-lipid disorder with the prevalence of type 2 diabetes mellitus(T2DM) and sex in the people of Nanning city,Guangxi province.Methods The 1072 people were divided into T2DM group and control group.Total cholesterol(TC),Triglyceride(TG),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C) and some other related indexes were measured in the patients group(n=411) and the control group(n=661).The result between the two groups were compared.Results ①In comparison with control group,TC,TG and HDL-C of patients with T2DM were significantly higher(P=0.0081、0.0015、<0.0001 respectively).②TG and TC were risk factors of T2DM for both male and female,high TC was more related to the male in prevalence of T2DM than female(OR 1.93:1.49)and high TG was more related to female(OR 2.49:1.46).Conclusions Lipids disorders is commonly existed in diabetic patients,and related to sex.
【Key words】 Blood-lipid disorder diabetes; DM; Triglyceride(TG); Total cholesterol(TC); LDL; HDL;
- 【文献出处】 中国老年保健医学 ,Chinese Journal of Geriatric Care , 编辑部邮箱 ,2009年01期
- 【分类号】R589;R587.1
- 【被引频次】2
- 【下载频次】204