【摘要】 目的观察神经妥乐平行星状神经节阻滞(SGB)的镇痛效果和不良反应。方法选择头面部、上肢及胸背部带状疱疹后神经痛患者74例。随机分为2组,分别采用神经妥乐平和1%利多卡因进行SGB。在每次阻滞前、阻滞后15 min观察2组收缩压、舒张压、心率;治疗前及治疗后12、、34、、8周的视觉模拟评分(VAS)和睡眠质量评分(QS)。结果SGB后15 min 2组血压、心率均下降,2组间差异无统计学意义。神经妥乐平组治疗前VAS为8.84±0.66,QS为3.78±0.31;治疗8周后VAS评分和QS评分均明显降低分别为1.11±0.38和0.22±0.13,与治疗前比较有高度统计学意义(P<0.01),与利多卡因组比较,差异有统计学意义(P<O.05)。结论采用神经妥乐平和1%利多卡因行SGB对治疗带状疱疹后神经痛均有治疗作用,且前者止痛效果优于后者,而且霍纳综合征发生率低,对缓解带状疱疹后神经痛和改善睡眠质量疗效显著;因此是临床治疗本病的较满意方法。更多还原

【Abstract】 AIM To observe the efficacy and adverse drug reactions of stellate ganglion block(SGB) with neurotropin intervention in the residual post-herpetic neuralgia(PHN).METHODS Seventy-four patients(aged 55-87 years)suffering from residual PHN were selected and divided into two groups randomly,and received SGB respectivelly with neurotropin and 1% lidocaine.Before and 15 min after SGB,BP and HR were observed.The clinical effect was evaluated before and after treatment by visual analogue scale(VAS)and quality of sleep(QS).RESULTS VAS and QS were 8.84±0.66 and 3.78±0.31 before treatment,and 1.11±0.38 and 0.22±0.13 after treatment in treatment group.There were significant differences(P<0.01).CONCLUSION The clinical effect of SGB with neurotropin is efficient on relief of PHN and improvement of quality of sleep.This therapy is safe for patients.更多还原